MGRC

Demonstrative Case Studies 1 and 2 provide a comprehensive overview of the optimisation and integrated use of MGRC analysis tools and services. MGRC utilises Synamatix technologies, which centre on SynaBASE, its core IP and novel structured network pattern database platform. The following case studies serve as an introductory guide on how best to apply and optimise the use of MGRC’s online bioinformatics applications:

	Case Study 1 Integrated applications for interrogating a structured network database for genomics research
	Case Study 2 A unique web-based application for scalable and rapid comparative genomics

The following monthly Application Notes are white papers based on on-going research activities conducted by the in-house bioinformatics development team. These Application Notes
provide in-depth understanding of SynaBASE’s unique pattern storage capabilities and the benefits of an integrated suite of ultra-fast analysis tools in a wide array of genomics
research areas.

	October 2005 “A global assesment of microarray probe set quality using genome and transcriptome data verification”
	September 2005 “Identification of protein families and their members using SIGNIFICANCE of patterns in a structured network pattern database”
	August 2005 “Nucleotide searches: Synasearch-Bulk demonstrates a 50 to 500 fold performance improvement and increased sensitivity over NCBI-BLAST”
	June 2005 “Utilisation of a novel structured network database in efficient storage and management of genomics data”
	May 2005 “Application of subsequence predictability in a structured network database for de novo gene prediction”
	April 2005 “Phylogenetics of whole genomes using a structured subsequence database approach”
	March 2005 “Reannotation of human liver transcipts from genome tiling microarrays reveals the location of functionally significant regions in the human genome”
	February 2005 “Our Roadmap Forward for 2005”