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October 2014

Gene Responsible for Traits Involved in Diabetes Discovered

A collaborative research team led by the Medical College of Wisconsin scientists has identified a new gene, called Tpcn2, which is associated with fasting glucose and insulin levels in humans, rats and mice. Tpcn2 is a lysosomal calcium channel that likely plays a role in insulin signalling. Glucose tolerance, insulin resistance and beta cell dysfunction are key underlying causes of type 2 diabetes.

Full story

Publications

• Gene That Increases Incidence of Acute Myelogenous Leukaemia Discovered
• Melanoma Risk Found to Have Genetic Determinant
• Illumina Says 228,000 Human Genomes Will be Sequenced This Year

News

• The Genome Assembly Archive: A New Public Resource
• Gatekeepers or Intermediaries? The Role of Clinicians in Commercial Genomic Testing
• Medical Genomics: The Intricate Path From Genetic Variant Identification to Clinical Interpretation

Blogs

• Return of Results: Genetics Experts Weigh in
• Learning to Use Genomics Safely, to Improve Children’s Health

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Genetic tests and related services are strictly for use by doctors only. Should you have questions about using these tests, please consult your doctor.