February 2014
Opening ‘the X-files’ Helps Researchers to Understand Why Women and Men
Differ in Height
Researchers have identified novel X-chromosomal genetic variants that influence human height. The study showed that a genetic variant close to ITM2A is frequent among individuals who are shorter than average. The identified variant was also shown to increase the expression of ITM2A, suggesting that the more the gene is expressed, the shorter the person will be. Interestingly, the effect of this variant on height was shown to be much stronger in women.
Publications
- Comparison of Three Next-Generation Sequencing Platforms for Metagenomic Sequencing and Identification of Pathogens in Blood
- Genome-Wide Linkage, Exome Sequencing and Functional Analyses Identify ABCB6 as the Pathogenic Gene of Dyschromatosis Universalis Hereditaria
- A Pan-Cancer Analysis of Transcriptome Changes Associated With Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events
- Major Aging-Associated RNA Expressions Change at Two Distinct Age-Positions
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