DECEMBER 2010
A team led by researchers at the National Human Genome Research Institute (NHGRI) has captured the most comprehensive snapshot to date of DNA regions that regulate genes in human pancreatic islet cells, a subset of which produces insulin. The study highlights the importance of genome regulatory sequences in human health and disease.
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- C. elegans mutant identification with a one-step whole-genome-sequencing and SNP mapping strategy
- Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer
- SeqEM: an adaptive genotype-calling approach for next-generation sequencing studies
- An evolutionary framework for association testing in resequencing studies
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