October 2014

A collaborative research team led by the Medical College of Wisconsin scientists has identified a new gene, called Tpcn2, which is associated with fasting glucose and insulin levels in humans, rats and mice. Tpcn2 is a lysosomal calcium channel that likely plays a role in insulin signalling. Glucose tolerance, insulin resistance and beta cell dysfunction are key underlying causes of type 2 diabetes.

September 2014

Researchers from the Broad Institute and Harvard University, in collaboration with the Sierra Leone Ministry of Health and Sanitation and other researchers across institutions and continents, have rapidly sequenced and analysed more than 99 Ebola virus genomes. Their findings could have important implications for rapid field diagnostic tests to combat the unprecedented Ebola outbreak in West Africa.

February 2014

Opening ‘the X-files’ Helps Researchers to Understand Why Women and Men

Differ in Height

Researchers have identified novel X-chromosomal genetic variants that influence human height. The study showed that a genetic variant close to ITM2A is frequent among individuals who are shorter than average. The identified variant was also shown to increase the expression of ITM2A, suggesting that the more the gene is expressed, the shorter the person will be. Interestingly, the effect of this variant on height was shown to be much stronger in women.
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