MGRC Offers Enhanced Online Sequence Analysis Tools

Improved version helps researchers with more complex bioinformatics analysis

Kuala Lumpur, 8 August 2011 – Malaysian Genomics Resource Centre Berhad (MGRC) has announced the extensive update of its comprehensive range of high-speed online bioinformatics analysis tools and reference databases. These free-to-use tools now offer users greater flexibility to perform complex analyses of genomic data with a very short turnaround time.

One of the major updates involves the seamless integration between SynaBlast-Mega and sequence data from NCBI’s GenBank database. MGRC’s SynaBlast-Mega bulk alignment tool enables users to search thousands of either nucleotide or protein sequences in a single submission. The tool now utilises the fullest set of DNA and protein sequences from GenBank. With this enhancement, SynaBlast-Mega users are able to submit up to 10MB of sequence query data, thus empowering them to analyse thousands of queries at one time.

To further improve its bioinformatics applications, MGRC has also included additional biological domains in its reference databases. While retaining a focus towards mammalian genomic information, complete datasets from fungal, bacterial, plant and invertebrate genomes have also been included. This Malaysia-based genome sequencing and analysis centre now operates with a storage capacity of more than 50 TB, as part of its commitment to provide state-of-the-art online sequence analysis tools to users throughout the world. The combination of integrated software tools and increased databases has seen a continued upswing in MGRC users from the United States, Europe, China and India. MGRC has also provided a version of the portal in Mandarin for Chinese users.

MGRC’s Chief Scientific Officer, Dr Stephen Rudd, explained, “The ability to easily perform complex searches and analyses of multiple sequences simultaneously using SynaBlast-Mega will greatly reduce the time taken by users to obtain results. Coupled with access to GenBank databases, our bioinformatics tools are primed to help scientists, researchers and bioinformaticians accelerate their downstream research and subsequently to make interesting new discoveries that are of significance. MGRC’s online applications are designed to be highly robust, versatile and all-encompassing. Much thought is also put into ensuring they are compatible with GenBank and other publicly-available reference databases, as well as being user-friendly.”

The enhanced and updated SynaBlast-Mega, and other online sequence analysis tools, can be freely accessed by the public at MGRC’s bioinformatics portal, www.mgrc.com.my.

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